Cajun-Style Seafood Alfredo with Lobster, Crab, and Salmon

Cajun-Style Seafood Alfredo with Lobster, Crab, and Salmon (Mediterranean-Inspired)

Table of Contents

This Cajun-Style Seafood Alfredo brings together tender lobster, sweet crab, and flaky salmon in a creamy, spicy, and garlicky Alfredo sauce. Infused with Mediterranean flavors and a Cajun kick, it’s a luxurious and comforting dish perfect for special occasions or a gourmet weeknight dinner.

Prep Time: 15 minutes

Cook Time: 20 minutes

Total Time: 35 minutes

Ingredients

For the Seafood:

1 lobster tail, shell removed and cut into chunks

½ cup lump crab meat (fresh or canned, drained)

1 salmon fillet (6 oz), skin removed and cut into bite-sized pieces

1 tablespoon Cajun seasoning

1 tablespoon olive oil

1 tablespoon butter

2 cloves garlic, minced

For the Cajun Alfredo Sauce:

2 tablespoons butter

3 cloves garlic, minced

1 ½ cups heavy cream (or half-and-half for a lighter option)

1 cup grated Parmesan cheese

1 teaspoon Cajun seasoning (adjust to taste)

½ teaspoon smoked paprika

½ teaspoon red pepper flakes (optional, for extra spice)

Salt & black pepper, to taste

¼ cup pasta water (reserved)

For the Pasta:

12 oz fettuccine (or pasta of choice)

1 tablespoon salt (for boiling water)

For Garnish:

2 tablespoons fresh parsley, chopped

Lemon wedges

Extra Parmesan cheese

Instructions

Cook the Pasta

Bring a large pot of salted water to a boil. Cook the fettuccine according to package instructions until al dente.

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Reserve ¼ cup of pasta water before draining.

Cook the Seafood

In a large pan, heat olive oil and butter over medium heat.

Season the salmon, lobster, and crab meat with Cajun seasoning.

Cook the salmon pieces for 3-4 minutes per side until golden brown and flaky. Remove and set aside.

In the same pan, add the lobster chunks and sauté for 3 minutes until opaque. Stir in the crab meat and minced garlic, cooking for another 2 minutes. Remove and set aside.

Make the Cajun Alfredo Sauce

In the same pan, melt 2 tablespoons of butter over medium heat.

Add minced garlic and sauté for 1 minute until fragrant.

Pour in the heavy cream and bring to a gentle simmer. Stir in Cajun seasoning, smoked paprika, red pepper flakes (if using), salt, and black pepper.

Gradually whisk in Parmesan cheese, stirring until smooth and creamy. Add reserved pasta water if needed to loosen the sauce.

Combine & Serve

Add the cooked fettuccine to the sauce, tossing to coat evenly.

Gently fold in the cooked seafood, allowing it to warm through for 1-2 minutes.

Garnish with fresh parsley, extra Parmesan, and a squeeze of lemon.

Serve immediately with crusty bread or a side salad.

Tips & Variations

Lighter Option – Use half-and-half instead of heavy cream and reduce butter.

Extra Spice? – Increase Cajun seasoning or add cayenne pepper.

More Mediterranean Flair? – Add sun-dried tomatoes, olives, or a drizzle of lemon zest-infused olive oil.

Gluten-Free? – Use gluten-free pasta.

Make-Ahead? – Prep the seafood and sauce separately and combine when ready to serve.

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Nutritional Value (Per Serving – Approximate, Based on 4 Servings)

Calories: ~650-750 kcal

Protein: ~45g

Carbohydrates: ~50g

Fats: ~35g

Saturated Fat: ~18g

Fiber: ~3g

Sugar: ~3g

Sodium: ~750-900mg (varies based on seasoning and cheese)