Mediterranean Cheesy Brussels Sprouts, Sweet Potato, Butternut Squash, Carrot & Beet Medley Casserole
This Mediterranean Cheesy Vegetable Medley Casserole is a comforting, colorful dish that brings together some of the best vegetables of the season in one warm, satisfying bake. Roasted Brussels sprouts, sweet potato, butternut squash, carrots, and beets create a naturally sweet and earthy base, while a light Mediterranean-style cheese layer adds richness without overwhelming the vegetables. This casserole works beautifully as a vegetarian main or as a hearty side for family dinners, gatherings, or meal prep. It feels indulgent, yet it is packed with fiber, vitamins, and slow-digesting carbohydrates that keep you full and energized.
Preparation Time: 20 minutes
Cooking Time: 45 minutes
Total Time: About 1 hour 5 minutes
Ingredients
Vegetables
2 cups Brussels sprouts, halved
1 large sweet potato, peeled and cubed
2 cups butternut squash, cubed
2 medium carrots, sliced
1 medium beet, peeled and cubed
Seasoning and Base
3 tablespoons olive oil
1 teaspoon paprika
½ teaspoon dried thyme
½ teaspoon dried oregano
Salt and black pepper, to taste
Cheesy Layer
1 cup grated mozzarella or mild cheddar
½ cup crumbled feta cheese
¼ cup grated Parmesan cheese
Optional Add-Ins
2 cloves garlic, minced
2 tablespoons chopped fresh parsley or basil
Instructions
Preheat the oven to 200°C (400°F) and lightly grease a large baking dish.
In a large bowl, combine Brussels sprouts, sweet potato, butternut squash, carrot, and beet.
Drizzle the vegetables with olive oil and sprinkle with paprika, thyme, oregano, salt, and pepper.
Toss everything well until the vegetables are evenly coated.
Spread the vegetables in a single layer on a baking tray and roast for 25 minutes.
Remove from the oven and transfer the partially roasted vegetables to the prepared baking dish.
Sprinkle garlic evenly over the vegetables if using.
Add mozzarella, feta, and Parmesan evenly over the top.
Return the dish to the oven and bake for another 20 minutes until bubbly and golden.
Remove from the oven, garnish with fresh herbs, and rest for 5 minutes before serving.
Tips
Cut vegetables into similar sizes for even roasting.
Roast vegetables first to prevent a watery casserole.
Use parchment paper to reduce sticking.
Balance sweet vegetables with enough seasoning.
Do not overload with cheese to keep it light.
Add garlic after initial roasting to avoid burning.
Let the casserole rest to set before serving.
Use freshly grated cheese for better melting.
Season vegetables before roasting, not after.
Taste and adjust salt based on cheese saltiness.
Variations
Add cooked lentils for extra protein.
Swap mozzarella for provolone or gouda.
Add chopped spinach during the final bake.
Use goat cheese instead of feta.
Sprinkle crushed walnuts for crunch.
Add chili flakes for gentle heat.
Replace beet with parsnip if preferred.
Use rosemary instead of thyme.
Add a light yogurt drizzle before serving.
Turn it vegan with plant-based cheese.
Q&A
Can I make this casserole ahead of time?
Yes, assemble and refrigerate, then bake when ready.
Is this dish freezer-friendly?
It freezes well without the cheese topping.
Can I use frozen vegetables?
Fresh works best, but frozen can be roasted first.
Is this suitable for weight management?
Yes, it is filling, fiber-rich, and balanced.
Can I reduce the cheese?
Yes, the dish still works with less cheese.
What protein pairs well with this?
Grilled chicken or baked fish are great options.
How long does it keep in the fridge?
Up to 3 days in an airtight container.
Can I make it dairy-free?
Use dairy-free cheese alternatives.
Why roast before baking?
It enhances flavor and prevents sogginess.
Can kids enjoy this?
Yes, the natural sweetness makes it kid-friendly.
Nutrition
(Approximate per Serving)
Calories: 380–420
Protein: 15–17 g
Carbohydrates: 40–45 g
Fiber: 8–10 g
Fat: 18–20 g
Rich in vitamin A, vitamin C, and calcium
Conclusion
This Mediterranean Cheesy Brussels Sprouts, Sweet Potato, Butternut Squash, Carrot & Beet Medley Casserole is a beautiful example of how vegetables can shine in a comforting, oven-baked dish. The combination of roasted sweetness, savory herbs, and melted cheese creates a balanced meal that feels nourishing and satisfying. Whether served as a vegetarian main or alongside your favorite protein, this casserole is easy to prepare, flexible, and perfect for sharing. It is a dish you can enjoy any time of year and return to whenever you want something wholesome and comforting without feeling heavy.